Shinwa Chemical Industries Ltd.
LC/GC Search / Application Note

Analysis of underivatized amino acids by LC/MS/MS

Graph

LC

Samples
(CYS)2 , LYS , ARG , HIS , ASP , GLU , GLN , ASN , GLY , SER , ALA , THR , PRO , TYR , VAL , PHE , MET , TRP , LEU+ILE
Applications
Analysis of underivatized amino acids by LC/MS/MS
Column
ULTRON AF-HILIC-CD (PLSS)
Column Size
150 mm L × 2.0 mm I.D.
Detector
LC/MS/MS (ESI, Positive, MRM)
Particle Size
2 µm
Mobile phase
A: 100 mM HCO2NH4(pH 3.0)/CH3CN = 10/90, B: 100 mM HCO2NH4(pH 3.0)/CH3CN = 70/30
Frow rate
0.36 mL/min
Gradient
20 minutes gradient, 88% - 60% with 10 minutes re-equilibration
TimeProfile
(min)%A%B
0.00 96 4
20.00 50 50
20.01 96 4
30.00 96 4
Column temp.
40°C
Injection volume
1.0 µL (5.0 µg/mL)

Price list

lc_00228