Shinwa Chemical Industries Ltd.
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Analysis of Oligo-deoxythymidine using the ULTRON AF-HILIC-CD “Effect of the type of salt and ionic strength in the mobile phase”

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LC

Samples
Oligo deoxythymidine primers, 6-25 mer
Applications
Analysis of Oligo-deoxythymidine using the ULTRON AF-HILIC-CD “Effect of the type of salt and ionic strength in the mobile phase”
Column
ULTRON AF-HILIC-CD
Column Size
150 mm L × 2.0 mm I.D.
Detector
UV-260 nm
Particle Size
2 µm
Frow rate
0.15 mL/min
Column temp.
30°C
Injection volume
0.5 µL
Diluent
CH3CN/TE buffer* = 70/30

Mobile phase
1.
A) CH3CN
B) 20 mM CH3CO2NH4
30-33 %B(0-3 min), 33 %B(3-20 min), 30 %B(20-40 min)
2.
A) CH3CN
B) 50 mM CH3CO2NH4
30-36 %B(0-6 min), 36-40 %B(6-27min), 30 %B(27-40 min)
3.
A) CH3CN
B) 100 mM CH3CO2NH4
30-36 %B(0-6 min), 36-42 %B(6-27min), 30 %B(27-40 min)
4.
A) CH3CN/20 mM KH2PO4-K2HPO4(pH 6.5) = 70/30
B) CH3CN/20 mM KH2PO4-K2HPO4(pH 6.5) = 30/70
0-9 %B(0-8 min), 9-12 %B(8-30min), 0 %B(30-40 min)

* TE buffer = 10 mM Tris-HCl buffer pH 8.0 + 1 mM EDTA buffer pH 8.0

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