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Chiral Separation Chromatography

The ULTRON ES series consists of columns designed specifically for chiral separations that employ chemically immobilized protein (ULTRON ES-OVM, ULTRON ES-PEPSIN, ULTRON ES-BSA) and cyclodextrin (ULTRON ES-CD, ULTRON ES-PhCD) stationary phases.

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ULTRON ES-OVM-3

To the application of this productReference

Features

  1. Maximum operating pressure of 30 MPa.
  2. Can be used in LC/MS systems as well.
  3. Employs a 3 µm packing material for higher peak resolution and theoretical plate numbers.
  4. Enables significant reductions in analysis times while maintaining high theoretical plate numbers.
  5. Enables further improvements in performance with optimization of LC system tubing and flow cells.
  6. 9 column length and inner diameter combinations available.

ULTRON ES-OVM-3 Lineup

Applications Semimicro-LC Semimicro-LC
Conventional-LC
Conventional-LC
Column Size
Length x I.D. (mm)
50 x 2.150 x 3.050 x 4.6
100 x 2.1100 x 3.0100 x 4.6
150 x 2.1150 x 3.0150 x 4.6

Applications

・Pharmaceuticals ・Pesticides ・Organic synthetic compounds

ULTRON ES-OVM, ULTRON ES-OVM-C

To the application of this productReference

Features

  1. Employ a highly denaturation resistant protein (ovomucoid) ligand.
  2. Display a wide range of chiral recognition.
  3. No sample pretreatment required for chiral separations.
  4. Can be used for reversed-phase analyses.
  5. Trace analyses possible (several nanograms).

  6. [ULTRON ES-OVM-C]
    Clopidogrel bisulfate evaluation conditions based on USP standards employed for shipping inspections.

  7. [ULTRON ES-OVM-C]
    Low viscosity 30% acetonitrile aqueous solution used as column storage solvent.

Applications

・Pharmaceuticals ・Pesticides ・Organic synthetic compounds

ULTRON ES-PEPSIN

To the application of this productReference

Features

  1. Employs the polypeptide splitting enzyme pepsin (obtained from pig stomach linings), which is chemically bonded to the base material in an extremely stable manner.
  2. Displays superior performance with respect to chiral separations of aminoalcohol pharmaceuticals such as beta blockers.
  3. No sample pretreatment required for chiral separations.
  4. Can be used for reversed-phase analyses.
  5. Trace analyses possible (several nanograms).

Applications

・Pharmaceuticals ・Pesticides ・Organic synthetic compounds

ULTRON ES-BSA

To the application of this productReference

Features

  1. Employs bovine serum albumin, which is chemically bonded to the base material in an extremely stable manner.
  2. Provides superior chiral separations of acidic compounds such as arylpropionic acid pharmaceuticals.
  3. No sample pretreatment required for chiral separations.
  4. Can be used for reversed-phase analyses.
  5. Trace analyses possible (several nanograms).

Applications

・Pharmaceuticals ・Pesticides ・Organic synthetic compounds

ULTRON ES-CD, ULTRON ES-PhCD

ULTRON ES-CD and ULTRON ES-PhCD columns are chiral separation columns employing chemically bonded beta-cyclodextrin (CD) and a beta-cyclodextrin derivative (PhCD) as stationary phases.

To the application of this productReference

Features

  1. Capable of chiral separations of hydrophobic cyclic compounds.
  2. Both reverse and normal phase eluents can be used.
  3. Chiral separations of a wide range of compounds are possible using these two types of columns.
  4. Display superior stability and durability.

Applications

・Pharmaceuticals ・Pesticides ・Organic synthetic compounds

※Please contact us for application data sheets containing examples of separations of optical isomers obtained using ULTRON ES-OVM, ES-CD, ES-PhCD, ES-PEPSIN, and ES-BSA columns.

PDF DownloadChiral Separation Chromatography: Specifications and Prices

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