ULTRON ES-OVM / ULTRON ES-OVM-C / ULTRON ES-OVM-M

Features

• Employs the protein ovomucoid as the stationary phase.
• Enables separations of a wide variety of compounds ranging from basic to acidic.
• Can be used for reversed-phase analyses.
• Suitable for trace analyses.
• Designed to confirm separations of Clopidogrel bisulfate (USP) [ULTRON ES-OVM-C]
• Designed to confirm separations of Escitalopram oxalate (USP) [ULTRON ES-OVM-E]
• Corresponded to L57

Comparison data between 5 μm and 3 μm

LC/MS analysis example

This column can be used for analyses for LC/MS employing volatile buffers such as ammonium acetate or ammonium formate.

Direct injection of a sample containing HSA

It is possible to separate optical isomers of Ketoprofen in HSA-containing samples even on direct injection of untreated samples without adverse effects due to HSA. In addition, as the ovomucoid stationary phase is a trypsin inhibitor, adverse effects due to samples containing trypsin are also kept to a minimum, making it suitable for analyses of biological samples.

ULTRON ES-OVM / ULTRON ES-OVM-C / ULTRON ES-OVM-E

ULTRON ES-PEPSIN

Features

• Employs pepsin, which is a polypeptide-digesting enzyme of pig stomach mucous membrane origin as the stationary phase.
• Effective for the enantiomer separation of amino alcohols such as β-blocker medicines.
• Can be used for reversed-phase analyses.
• Suitable for trace analyses.

ULTRON ES-BSA-2

Features

1. Employs BSA, which is a bovine serum albumin as the stationary phase.
2. Effective for the enantiomer separation of acidic compounds such as allylpropionic acid drugs.
3. No sample preparation is required for chiral separation.
4. Can be used for reversed-phase analyses.
5. Suitable for trace analyses.
6. Corresponded to L75

Methotrexate (USP)

Sulindac

Ketoprofen

ULTRON ES-CD / ULTRON ES-CD-2 / ULTRON ES-PhCD

Features

• Employs the β-cyclodextrin (CD) and phenylcarbamated β-cyclodextrin (PhCD), respectively.
• Capable of chiral separations of hydrophobic cyclic compounds.
• Both reverse and normal phase eluents can be used.
• Corresponded to L45
• ULTRON ES-CD-2 is an up-graded version of ULTRON ES-CD with good scalability.

Scalability application

Comparison data between ES-CD and ES-CD-2

ULTRON ES-CD / ULTRON ES-CD-2 / ULTRON ES-PhCD

ULTRON ES-CD-EP

The ULTRON ES-CD-EP corresponds to L45, has been confirmed to meet the System suitability in accordance with USP under strict quality control.
In the USP, L45 column (3 μm) for the evaluation of enantiomeric purity of Epinephrine injection is specified.

ULTRON ES-CD-F

The ULTRON ES-CD-F corresponds to L45, has been confirmed to meet the System suitability accordance with USP under strict quality control.
In the USP, L45 column (5 μm) for the evaluation of Fexofenadine is specified.

ULTRON ES-CD-B

The ULTRON ES-CD-B has been confirmed to meet the System suitability accordance with JP under strict quality control.
In the JP, β-cyclodextrin column (5 μm) for the evaluation of enantiomer of Bepotastine besilate is specified.